What do the following biblical characters have in common apart from the fact that their related by blood; Adam, Seth, Enosh, Kenan, Mahalalel, Jared, Enoch, Methuselah, Lamech and Noah? They are also known as the Antediluvian Patriarchs, which translates as Scriptural Fathers of the Pre-Flood Age. According to the bible, they all lived to be a couple of hundred years old. That was my first thought when I read the synopsis of a TED talk under the theme; “Might you live a great deal longer?”
This is the final post on an unintentional series about ageing. I have written about immortality, the youth culture and the final act. Today’s post looks at Aubrey de Grey’s assertion that the first human beings to live to a 1000 years have already been born. The British researcher on gerontology claims that we need to develop treatments that repair the damage caused by ageing and thereby delaying pathology. Below you will find the video of his TED talk. However be warned that he talks really fast and packs a whole lot of information into 18 minutes.
Basically Aubrey claims that ageing leads to pathology because of physical damages accumulating in our body. He identifies 7 areas where this damage occurs; Cell loss/atrophy, Death-resistant cell, Nuclear Mutations and Epimutations, Mt DNA mutations, Protein crosslinks, Junk inside cells and Junk outside cells. (These points were listed on a slide Aubrey used during the talk – 16th minute.) I need an encyclopaedia to make sense of some of these points. But the gist of it is metabolism damages our cellular structures, which culminates in death.
Aubrey proposes that it is possible to repair the damage through treatments. He says that anti-ageing treatments would keep improving and treat people before they enter the certain death phase and thereby increasing their life duration century by century. As a result of these continuous treatment improvements it would be possible to reach a life span of a thousand years. However we need to invest in the research of such treatments immediately, if we want to experience longevity to this extent.
In the Q&A session after the talk, Aubrey stressed that ageing is not the result of selection. In his opinion, evolution has neglected to find a way to resolve mortality because it would require too much energy and more sophisticated genes. In other words, if evolution were more hardworking we probably would be immortals by now.
This brings me back to the topic of the Antediluvian Patriarchs. I probably would get to hear that the bible is a fictional work and thus not a fitting reference when trying to find answers to a scientific question. Since this is my post, we will stick to the assumption that the Antediluvian Patriarchs had existed. The last of this group, Noah, supposedly lived up to 950 years. Therefore according to the bible, men started out with life spans of almost 1000 years. However after Noah, the life span continually decreased until King Solomon only lived to be about 70 years old. According to WHO statistics from the year 2009 the median life expectancy is at 71 years. It would seem that human life expectancy has been constant for thousands of years.
Why has the time we spend on earth shortened after Noah? It would appear that sin and men distancing themselves from God led to a drastic cleansing through the flood. Noah was the chosen one to start a new civilisation on earth. However this new world became tainted by sin too.
Since I believe in the existence of God, I do not find it too farfetched to assume that God’s original creation had very sophisticated genes. However the quality of genes deteriorated overtime as a result of our indulgence in activities harmful to our physical wellbeing. Therefore I think it is plausible to undo these damages through advanced medical treatments.
Do I think this is the right time to invest in such medical treatments? No. In my opinion, if such treatments were available now, it would only benefit the rich. After all, we have vaccinations for diseases that still kill thousands of children in the third world country. The reason for their death is lack of money, which bars their access to the medication. Thus you can imagine how it would be, if it were possible to live for centuries. It would be naive to assume that such treatments would be free of charge.
What do you think?